Diagnostic protocol for pancreatic neuroendocrine tumors (PNETs).

نویسندگان

  • Modesto Varas
  • Joan Gornals
  • José Luis Prieto
  • Julio Iglesias-García
چکیده

A: angiography; US: ultrasonography; EUS: endoscopic ultrasonography; IUS: intraoperative ultrasonography; EUS-FNA: endoscopic ultrasonography-guided fine-needle aspiration; MRI: magnetic resonance imaging; SRS: octreoscan; CT: computerized tomography; MDCT: multidetector computerized tomography; PET: positron emission tomography; PET-CT: PET with computerized tomography; ICC: immunocytochemistry; I: insulinoma; G: gastrinomas; PNET: pancreatic neuroendocrine tumor or apudoma; NF-PNET: non-functioning PNET; MEN: multiple endocrine neoplasia; VHL: von Hippel-Lindau disease; R: review; C: cystic; CE: contrast-enhanced.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Diagnosis of Pancreatic Neuroendocrine Tumors

Pancreatic neuroendocrine tumors (PNETs) are relatively rare; however, the incidence has increased over the last few decades. They are classified as functional or non-functional tumors according to the presence of associated clinical symptoms. The majority are non-functional tumors. For classification and staging, the World Health Organization 2010 classification system is the most commonly acc...

متن کامل

Chromogranin A is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumors but not for insulinomas

BACKGROUND Pancreatic neuroendocrine tumors (PNETs) are a group of rare tumors. Chromogranin A (CgA) was considered as the most practical and useful serum tumor marker in PNET patients. But peripheral blood levels of CgA are not routinely tested in Chinese patients with PNETs. This study was to assess the diagnostic value of CgA in Chinese patients with PNETs especially in patients with insulin...

متن کامل

Identification of novel serum autoantibodies against EID3 in non-functional pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumors (pNETs) are relatively rare heterogenous tumors, comprising only 1-2% of all pancreatic neoplasms. The majority of pNETs are non-functional tumors (NF-pNETs) that do not produce hormones, and as such, do not cause any hormone-related symptoms. As a result, these tumors are often diagnosed at an advanced stage because patients do not present with specific symptom...

متن کامل

Pancreatic neuroendocrine tumors: biology, diagnosis, and treatment

Pancreatic neuroendocrine tumors (PNETs), a group of endocrine tumors arising in the pancreas, are among the most common neuroendocrine tumors. The genetic causes of familial and sporadic PNETs are somewhat understood, but their molecular pathogenesis remains unknown. Most PNETs are indolent but have malignant potential. The biological behavior of an individual PNET is unpredictable; higher tum...

متن کامل

Clinical relevance of different WHO grade 3 pancreatic neuroendocrine neoplasms based on morphology

PURPOSE Emerging evidence suggests G3 pancreatic neuroendocrine neoplasms (pNENs) present heterogeneous morphology and biology. The 2017 WHO classification has introduced a new category of well-differentiated pancreatic neuroendocrine tumors (WD-pNETs) G3, compared with poorly differentiated pancreatic neuroendocrine carcinomas (PD-pNECs) G3. We aim to analysis the demographics and outcomes of ...

متن کامل

Regression of a Glucagonoma-Related Paraneoplastic Optic Neuropathy after Surgical Resection

Pancreatic neuroendocrine tumours (PNETs) account for 5% of pancreatic tumours [1] and are malignant in 50-88% of cases [2]. PNETs can be functioning, i.e., with clinical manifestations due to hormonal hypersecretion, in about 30% of cases. The most frequent functioning PNETs are those related to hypersecretion of insulin and gastrin. Rarely, PNETs may be associated with VIPoma and glucagonoma ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

دوره 104 1  شماره 

صفحات  -

تاریخ انتشار 2012